
Jocelyn Chen
Contributor at HealthCanal
Articles
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1 month ago |
tandfonline.com | Jocelyn Chen |Gabriel Perez |Gabriel Pérez |Bradley Lin |Adam Witterstaetter
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Mar 26, 2025 |
science.org | Jitesh Neupane |Samuel Petshow |Yuzhe Yang |Jocelyn Chen
AbstractEmerging evidence has shown that epigenetic regulation plays a fundamental role in cancer metastasis, the major cause of cancer-related deaths. Here, we conducted an in vivo screen for vulnerabilities of brain metastasis and identified N-acetyltransferase 10 (NAT10) as a driver of brain metastasis. Knockdown of NAT10 restrains cancer cell proliferation and migration in vitro and tumor growth and brain metastasis in vivo.
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Nov 15, 2024 |
tandfonline.com | Audrey Chen |Jocelyn Chen |Sri Kowtha |Nitya Bhupathi Raju
Abraham model solute descriptors for 2‑[4-(dibutylamino)-2-hydroxybenzoyl]benzoic acid were determined from the compound’s published solubility data in 10 organic solvents of varying polarity and hydrogen-bonding character.
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Sep 16, 2024 |
mdpi.com | Jocelyn Chen |Audrey Chen |Yixuan Yang |William E. Acree
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Aug 21, 2024 |
biorxiv.org | Jocelyn Chen |Peng Xu |Wesley L. Cai |Huacui Chen
AbstractMetastasis is the major cause of cancer-related deaths. Emerging evidence has shown that epigenetic regulation plays a fundamental role in cancer metastasis. To better understand the epigenetic regulation of metastasis, we conducted an in vivo shRNA screen for vulnerabilities of brain metastasis and identified N-acetyltransferase 10 (NAT10) as a driver of brain metastasis.
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