Huanyu Qiao

Jan 28, 2024 | nature.com | Emily Kaye |Geoffrey Nelson |Huanyu Qiao |Karen Adelman |Kavyashree Basavaraju

AbstractMale germ cell development requires precise regulation of gene activity in a cell-type and stage-specific manner, with perturbations in gene expression during spermatogenesis associated with infertility. Here, we use steady-state, nascent and single-cell RNA sequencing strategies to comprehensively characterize gene expression across male germ cell populations, to dissect the mechanisms of gene control and provide new insights towards therapy.