Huaxiang Wu

2 months ago | onlinelibrary.wiley.com | Yifan Xie |Qi Cheng |Jing XUE |Huaxiang Wu

1 Introduction Itaconate as a metabolite also acts as an important signalling molecule in immune regulation. Itaconate has potent immunomodulatory activity and plays an important role in the regulation of energy metabolism, anti-inflammatory, antioxidant and various immune responses, as well as biological effects on almost all organs [1-7].