Jing XUE

Nov 25, 2024 | nature.com | Jing XUE |Yong Huei Wang

AbstractMammalian sodium-coupled high-affinity choline transporter CHT1 uptakes choline in cholinergic neurons for acetylcholine synthesis and plays a critical role in cholinergic neurotransmission. Here, we present the high-resolution cryo-EM structures of human CHT1 in apo, substrate- and ion-bound, hemicholinium-3-inhibited, and ML352-inhibited states. These structures represent three distinct conformational states, elucidating the structural basis of the CHT1-mediated choline uptake mechanism.

May 22, 2024 | dovepress.com | Tianyu Chen |Jing XUE |Qian Wang

Back to Journals » Clinical, Cosmetic and Investigational Dermatology » Volume 17 Authors Chen T , Xue J , Wang Q  Received 22 May 2024Accepted for publication 18 September 2024 Published 25 September 2024Volume 2024:17 Pages 2151—2163 DOI https://doi.org/10.2147/CCID.S479411Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 2 Editor who approved publication: Prof.

Feb 22, 2024 | journals.plos.org | Xiaobin Liu |Jing XUE |Ting Li |Zhejiang Sci-Tech

Citation: Liu X, Xue J, Li T, Wu Q, Sheng H, Yang X, et al. (2024) Quantitative detection and prognostic value of antibodies against M-type phospholipase A2 receptor and its cysteine-rich ricin domain and C-type lectin domains 1 and 6-7-8 in patients with idiopathic membranous nephropathy. PLoS ONE 19(2): e0298269. https://doi.org/10.1371/journal.pone.0298269Editor: Joseph J.

Jan 29, 2024 | dx.doi.org | Neng Jin |Jin Wu |Shuming Ye |Jing XUE

Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Appl. Mater. Interfaces 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).

Oct 4, 2023 | nature.com | Jing XUE |Scott A. John

AbstractNa+/Ca2+ exchangers (NCX) transport Ca2+ in or out of cells in exchange for Na+. They are ubiquitously expressed and play an essential role in maintaining cytosolic Ca2+ homeostasis. Although extensively studied, little is known about the global structural arrangement of eukaryotic NCXs and the structural mechanisms underlying their regulation by various cellular cues including cytosolic Na+ and Ca2+.