Yifan Xie

2 months ago | onlinelibrary.wiley.com | Yifan Xie |Qi Cheng |Jing XUE |Huaxiang Wu

1 Introduction Itaconate as a metabolite also acts as an important signalling molecule in immune regulation. Itaconate has potent immunomodulatory activity and plays an important role in the regulation of energy metabolism, anti-inflammatory, antioxidant and various immune responses, as well as biological effects on almost all organs [1-7].

Mar 23, 2025 | nature.com | Haotong Li |Chiyin Wang |Yifan Xie |Zhiwei Yang |Dongcheng Cai

AbstractPromoting endogenous cardiomyocyte proliferation is a promising strategy for cardiac repair. Identifying key factors that regulate cardiomyocyte proliferation can advance the development of novel therapies for heart regeneration. Here, we identify Foxk1 and Foxk2 as key regulators of cardiomyocyte proliferation, whose expression declines during postnatal heart development.

Feb 24, 2025 | advanced.onlinelibrary.wiley.com | Yuxuan Zhang |Yifan Xie |Hao Mei |Hui Yu

Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202416741-sup-0001-SuppMat.docx15.3 MB Supporting Information References 1, , , , Science 2004, 304, 84. 2a) , , , , , , , , J. Am. Chem. Soc. 2022, 144, 1119; b) , , , , , , , , , , , , , , , , Nat. Chem. 2017, 9, 1170. 3, , , , , , , , Nature 2022, 606, 507. 4a) , Nat. Mater. 2010, 9, 868; b) , , , Chem 2022, 8, 2079.

Feb 20, 2025 | mdpi.com | Xinghua Li |Yifan Xie |Yuntao Guo |Tianzuo Wang

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Dec 9, 2024 | mdpi.com | Yu Feng |Weiming Zeng |Yifan Xie |Hongyu Chen

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.