Hyungju Park

Sep 6, 2024 | biorxiv.org | Hyungju Park |Jeongho Han

AbstractBrain-derived neurotrophic factor (BDNF) plays an essential role in regulating diverse neuronal functions in an activity-dependent manner. Although BDNF is synthesized primarily in neurons, astrocytes can also supply BDNF through various routes, including the recycling of neuron-derived BDNF. Despite accumulating evidence for astrocytic BDNF uptake and resecretion of neuronal BDNF, the detailed mechanisms underlying astrocytic BDNF recycling remain unclear.

Jun 28, 2023 | frontiersin.org | Maria Mola |Hyungju Park |Ken Berglund

IntroductionOptogenetics is an innovative technology for controlling the complex nervous system, allowing for two-way interactions between neurons and glial cells. Numerous studies have shown that optogenetic treatment of neuronal cells promotes cell excitability (Adamantidis et al., 2007; Carter et al., 2010; Park et al., 2015; Hyung et al., 2019) and synaptic response (Lindsay et al., 2011; Mahn et al., 2016; Sinnen et al., 2017).