Ingrid E. Scheffer

Jul 4, 2024 | onlinelibrary.wiley.com | Elaine C. Wirrell |Lieven Lagae |Ingrid E. Scheffer |J. Helen Cross

Fenfluramine (FFA) is an antiseizure medication (ASM) used in the treatment of seizures associated with Dravet syndrome (DS) and Lennox–Gastaut syndrome (LGS). FFA is initiated at 0.2 mg/kg/day but speed of titration may depend on age, weight, and concomitant medications. FFA is generally well-tolerated and associated with a low risk of clinically relevant drug–drug interactions, which are often observed with polypharmacy.