Lieven Lagae

Jul 4, 2024 | onlinelibrary.wiley.com | Elaine C. Wirrell |Lieven Lagae |Ingrid E. Scheffer |J. Helen Cross

Fenfluramine (FFA) is an antiseizure medication (ASM) used in the treatment of seizures associated with Dravet syndrome (DS) and Lennox–Gastaut syndrome (LGS). FFA is initiated at 0.2 mg/kg/day but speed of titration may depend on age, weight, and concomitant medications. FFA is generally well-tolerated and associated with a low risk of clinically relevant drug–drug interactions, which are often observed with polypharmacy.

Aug 6, 2023 | onlinelibrary.wiley.com | Joseph Sullivan |Lieven Lagae |J. Helen Cross |Orrin Devinsky

RESEARCH ARTICLE This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/epi.17737. Abstract Objective To assess the safety and efficacy of fenfluramine in the treatment of convulsive seizures in patients with Dravet syndrome.