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Jul 6, 2024 | 
academic.oup.com | Humboldt-Universität zu Berlin |Metabolic Diseases |Charité Universitätsmedizin Berlin |IRCCS San Raffaele
Nucleic acid-based therapies are being rapidly developed for prevention and management of cardiovascular diseases (CVD). Remarkable advancements have been achieved in the delivery, safety, and effectiveness of these therapeutics in the past decade. These therapies can also modulate therapeutic targets that cannot be sufficiently addressed using traditional drugs or antibodies.
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May 24, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewPatients who undergo anterior vaginal wall plastic surgery and place the bladder catheter
during surgery are selected. The purpose of the study is to evaluate the presence of
statistically significant differences in bladder catheter repositioning within 12 hours after
bladder catheter removal in the group of patients in whom the bladder catheter is removed on
postoperative day I or II.
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May 16, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewProspective observational study designed to describe the clinical, laboratory, imaging,
microbiological characteristics and treatment of specific infectious diseases, with the
addition of a dedicated biobank.
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May 9, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewAt enrollment, after informed consent form will be discussed and signed, subjects will
undergo complete disease assessment.
In this study, 150 adult subjects with IBD will be enrolled at the Gastroenterology
Department of the San Raffaele Hospital (50 patients with Crohn's disease, 50 with Ulcerative
colitis not undergoing proctocolectomy, and 50 with Ulcerative colitis undergoing
proctocolectomy with ileal pouch-anal anastomosis).
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Apr 19, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewBrugada Syndrome (BS) is an inherited heart condition that can cause sudden cardiac arrest in
young individuals. It's diagnosed through specific changes seen on an electrocardiogram
(ECG). Currently, the only treatment option is a cardioverter defibrillator (ICD). Despite
advances, much about BS remains unclear, including its genetic basis. This study aims to use
advanced genetic sequencing and artificial intelligence to uncover new genetic factors
contributing to BS.
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Apr 17, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewThe study investigates the feasibility and the efficacy to treat pancreatic solid lesions as
pancreatic adenocarcinomas (PDAC) and neuroendocrine tumors (NET) with ex-vivo radiofrequency
ablation (RFA) under ultrasound (US) control.
The study intent is to define the optimal radiofrequency ablation POWER of the system in
terms of maximum sizes (diameters) of histological coagulative necrosis obtained at
pathological samples.
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Apr 17, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewThis project aims to evaluate the impact of the introduction of an au-tomated system for
radiopharmaceutical preparation and administra-tion on the radiation safety of the
radiographers working in nuclear medicine. This study will help to fill the existing gap in
the scientific literature and provide useful guidance for the selection of the safest and
most effective automated infusion system.
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Apr 15, 2024 | 
academic.oup.com | IRCCS San Raffaele
The importance of detecting and treating obesity in cardiological careObesity, characterized by an excessive accumulation of body fat, is a modifiable cardiovascular (CV) risk factor and a chronic disease marked by chronic inflammation and a heightened burden of cardiometabolic disorders. In May 2022, the World Health Organization (WHO) reported that 60% of European citizens are overweight or obese.
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Mar 23, 2024 | 
trialbulletin.com | IRCCS San Raffaele
Overview The goal of this observational study is to evaluate, retrospectively and prospectively, the effect of different hormonal and neuropeptide dysfunctions on the body composition of patients suffering from hypothalamic-pituitary pathologies, and to evaluate the potential beneficial effect of surgical and medical treatments with agonists and antagonists of hypothalamic neuropeptides, currently available, on the development and treatment of adiposity and its negative cross-talk with muscle...
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Mar 21, 2024 | 
trialbulletin.com | IRCCS San Raffaele
OverviewObservational study. Participants of the FRASNET study (9th March 2017, Protocol No.
24/INT/2017) who were evaluated in 2016 and 2017 will be contacted to be re-evaluated with
multidimensional visits as part of the present study in order to assess trajectories and
biomarkers of frailty and sarcopenia.
