Iskander Khusainov

Jun 5, 2024 | nature.com | Iskander Khusainov |Camille V. Goemans |Christian Zimmerli |Sonja Welsch |Julian D. Langer |Athanasios Typas

AbstractRibosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative bacteria are lacking, despite their ribosomes being major antimicrobial drug targets. Here we compare two E. coli strains, a lab E. coli K-12 and human gut isolate E.