Jacqueline E. Payton

1 month ago | nature.com | Jian Xu |Jay C. Nix |Michael Gross |Steven Brody |Gaya K. Amarasinghe |Jacqueline E. Payton

AbstractThe Mediator complex facilitates interactions between transcription factors and RNA polymerase II, a process that is required for host gene transcription, including in response to viral infections. Among the many subunits in the Mediator complex, the MED25 subunit has been shown to be a target for viral activators during infection.