Janna C. Minehart

1 month ago | cgtlive.com | Joseph A Fraietta |Janna C. Minehart |Caroline DiOrio |Noah Stansfield

0:00 – Intro and guest introduction 2:00 – Challenges in predicting toxicities in preclinical models 10:00 – How manufacturing parameter changes can affect toxicity rates 13:06 – Strategies for managing inflammatory toxicities in smaller medical centers 19:52 – Goal of decoupling treatment potency from toxicity 20:44 – Potential for future unknown toxicities in immunotherapies 24:52 – Challenges in defining and identifying immune effector cell-associated HLH-like syndrome (IEC-HS) biomarkers...

2 months ago | cgtlive.com | Joseph A Fraietta |Janna C. Minehart |Noah Stansfield

0:00 – Intro and guest introduction 6:12 – Challenges and Insights from Early Clinical Trials 8:15 – Innovations and Clinical Results 12:21 – Discussion on Antigen Expression and Readministration 18:22 – Adaptations and Future Directions 25:43 – Controversial Opinions and Final Thoughts We're excited to introduce another episode of the ImmunoLogic video podcast, hosted by Joseph Fraietta, PhD, an assistant professor of microbiology and the director of the Fraietta Lab at the University of...