Joseph A Fraietta

1 month ago | cgtlive.com | Joseph A Fraietta |Janna C. Minehart |Caroline DiOrio |Noah Stansfield

0:00 – Intro and guest introduction 2:00 – Challenges in predicting toxicities in preclinical models 10:00 – How manufacturing parameter changes can affect toxicity rates 13:06 – Strategies for managing inflammatory toxicities in smaller medical centers 19:52 – Goal of decoupling treatment potency from toxicity 20:44 – Potential for future unknown toxicities in immunotherapies 24:52 – Challenges in defining and identifying immune effector cell-associated HLH-like syndrome (IEC-HS) biomarkers...

2 months ago | cgtlive.com | Joseph A Fraietta |Janna C. Minehart |Noah Stansfield

0:00 – Intro and guest introduction 6:12 – Challenges and Insights from Early Clinical Trials 8:15 – Innovations and Clinical Results 12:21 – Discussion on Antigen Expression and Readministration 18:22 – Adaptations and Future Directions 25:43 – Controversial Opinions and Final Thoughts We're excited to introduce another episode of the ImmunoLogic video podcast, hosted by Joseph Fraietta, PhD, an assistant professor of microbiology and the director of the Fraietta Lab at the University of...

Jan 31, 2025 | cgtlive.com | Joseph A Fraietta |Noah Stansfield

0:00 – Intro and guest introduction 2:47 – Discussion on chemotherapy in lymphoma treatment 12:34 – Artificial intelligence in predicting lymphoma outcomes 19:30 – Lymphocyte fitness and CAR T-cell therapy 24:01 – Persistence and retreatment of CAR T-cells 31:22 – Disease control and tumor volume We're excited to introduce the ImmunoLogic video podcast, hosted by Joseph Fraietta, PhD, an assistant professor of microbiology and the director of the Fraietta Lab at the University of...

Jan 20, 2025 | nature.com | Joseph A Fraietta

Apr 23, 2024 | nature.com | Katherine Mueller |Andy Chen |Yingshi Chen |Bence Daniel |Jose Arias-Umana |Alice Wang | +10 more

Correction to: Nature https://doi.org/10.1038/s41586-024-07300-8 Published online 10 April 2024In the version of the article initially published, in the black violin plots in Fig. 5a, a dashed line was used to represent the mean and dotted lines for quartiles. This has now been corrected to a solid line for the mean and dashed lines for the quartiles in the HTML and PDF versions of the article.