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Jan 10, 2025 | 
link.springer.com | Japan Agency |Plateforme GENOMAX |Faculté de Médecine |Fédération Hospitalo-Universitaire OMICARE
AbstractThe optimal timing for initiating dialysis and prognostic markers in chronic kidney disease (CKD) patients are under debate, with mortality and cardiovascular risks varying among patients. This study investigates whether the apoptosis inhibitor of macrophage (AIM), which is mostly bound to pentameric IgM, could serve as an effective indicator. We prospectively followed 423 patients at dialysis initiation and 563 at various CKD stages.
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Nov 7, 2024 | 
molecular-cancer.biomedcentral.com | Transdisciplinary Research Initiatives |Japan Agency
This study was conducted on individuals who underwent colonoscopy at the National Cancer Center Hospital (NCCH), Tokyo, Japan, and the National Cancer Center Hospital East (NCCHE), Chiba, Japan.
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Nov 1, 2024 | 
academic.oup.com | Japan Agency
Almost all biological processes on Earth are driven by the energy supplied by sunlight. Chlorophyll-based photosystems convert sunlight energy into chemical energy through photosynthetic reactions, and this energy flows into ecosystems in the form of organic compounds. Cyanobacteria, one of the most abundant photosynthetic microorganisms utilizing chlorophyll-based photosystems, inhabit almost any light-exposed environment [1, 2].
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Sep 28, 2024 | 
academic.oup.com | Japan Agency
Growth via agglomeration in gentle pair-wise collisions constitutes the first step in the planet formation process (e.g. Drążkowska et al. 2023; Krijt et al. 2023). This process connects the (sub-)micron-sized grains and condensates that we see in, e.g. scattered light images to the larger macroscopic ‘pebbles’ seen in ALMA continuum images that are also the precursors of planetesimals in the streaming instability plus gravitational collapse scenario (Johansen et al.2014).
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Sep 18, 2024 | 01103-3&sz=64)
cell.com | Biomedical Research |Japan Agency
Keywords Lipid microbiome phospholipase polyunsaturated fatty acid short-chain fatty acid colon lipidome knockout mouse Research topic(s) CP: Metabolism Introduction The gastrointestinal tract harbors trillions of microorganisms, collectively known as the gut microbiota.1 Cohabitation of the commensal microbiota with cells that populate the intestinal epithelium plays a central role in host metabolism and immunity and acts as an important barrier that prevents invasion of pathogens across the...
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Sep 17, 2024 | 
link.springer.com | Transdisciplinary Research Initiatives |Japan Agency
AbstractInflammatory respiratory diseases, such as interstitial lung disease (ILD), bronchial asthma (BA), chronic obstructive pulmonary disease (COPD), and respiratory infections, remain significant global health concerns owing to their chronic and severe nature. Emerging as a valuable resource, blood extracellular vesicles (EVs) offer insights into disease pathophysiology and biomarker discovery in these conditions.
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Aug 29, 2024 | 
link.springer.com | Japan Agency
AbstractThe globalization and rapid advancements in medical technologies necessitate the harmonization of international regulatory frameworks to ensure the efficient and timely clinical application of medical products, including pharmaceuticals and medical devices.
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Mar 19, 2024 | 
academic.oup.com | Biomedical Engineering |Japan Agency
Multiple changes occur in hormonal regulation with aging and across various endocrine organs. These changes are associated with multiple age-related disorders and diseases. A better understanding of responsible underling biological mechanisms could help in the management of multiple endocrine disorders over and above hormone replacement therapy (HRT). Cellular senescence is involved in multiple biological aging processes and pathologies common in elderly individuals.
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Jan 15, 2024 | 00454-9&sz=64)
cell.com | Japan Agency
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Jan 13, 2024 | 
link.springer.com | Japan Agency
AbstractA novel mesophilic bacterial strain, designated S502T, was isolated from a deep-sea hydrothermal vent at Suiyo Seamount, Japan. Cells were Gram-positive, asporogenous, motile, and curved rods, measuring 1.6–5.6 µm in length. The strain was an obligate anaerobe that grew fermentatively on complex substrates such as yeast extract and Bacto peptone. Elemental sulfur stimulated the growth of the strain, and was reduced to hydrogen sulfide.
