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Sep 28, 2024 | 
medrxiv.org | Kevin Tang |Jeffrey Jones |Wenjun Fan |Nathan Wong
The authors have declared no competing interest. Support was provided by the Stanley S. Franklin MD Memorial Endowment Fund for Hypertension and Heart Disease Prevention Research from the University of California, Irvine. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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Jul 24, 2024 | 
bestbets.org | Jeffrey Jones
Three Part QuestionIn [adults with acute uncomplicated appendicitis] is [treatment with antibiotics comparable to appendectomy] in [improvement of pain and acute symptoms, hospital cost, and complication rate]? Clinical ScenarioA 34-year-old female presents to the Emergency Department with abdominal pain and nausea that started 1 day ago and became more intense and moved to the right lower quadrant. She is taking an oral contraceptive pill and has no known drug allergies.
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Jul 23, 2024 | 
bmcgenomics.biomedcentral.com | Aastha Subedi |Gerald V. Minsavage |Pamela Roberts |Erica Goss |Anuj Sharma |Jeffrey Jones
A total of 157 billion base pairs of sequence was generated across all samples using an Illumina NovaSeq X Plus sequencing platform, resulting in around 5.2 Gbp sequences per sample (Supplementary Table S1). On average, 85.56% of the reads were successfully mapped to the pepper reference genome Zunla-1 (Supplementary Table S1). A total of 27,826 genes were identified.
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Jun 12, 2024 | 
bestbets.org | Jeffrey Jones
Three Part QuestionIn [adult patients presenting with an acute hot joint] do [negative serum biomarkers] compared with [clinical assessment, synovial fluid microscopy and culture] rule out [septic arthritis]? Clinical ScenarioA 48-year-old male with a history of type 2 diabetes
presents to the emergency department with left knee pain. On examination, his left knee is erythematous with an effusion and tender to palpation. He is very
painful with both passive and active range of motion.
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Apr 6, 2024 | 
scnow.com | Jeffrey Jones
Details for PUBLIC STORAGE 2238 4935 SUNSET BLVD SUITE B, LEXINGTON, SC 29072
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Feb 29, 2024 | 
bestbets.org | Jeffrey Jones
Three Part Question[In adults with benign paroxysmal positional vertigo] [what treatment is most effective] at [symptom resolution]? Clinical ScenarioA 34-year-old female comes to the emergency department due to acute episodes of dizziness. The history and physical exam are most consistent with diagnosis of posterior canal benign paroxysmal positional vertigo (BPPV). You wonder what is the most effective treatment at resolving her symptoms.
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Feb 29, 2024 | 
bestbets.org | Jeffrey Jones
Three Part QuestionIn [emergency department patients with uncomplicated acute bronchitis], how does [administration of systemic steroids compared to supportive care alone] affect [duration of symptoms]? Clinical ScenarioA 60-year-old male with noncontributory past medical history presents with two weeks of productive cough. His initial course of illness included additional upper respiratory tract infection symptoms, all of which improved within the first five days apart from the cough.
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Feb 29, 2024 | 
bestbets.org | Jeffrey Jones
Three Part QuestionWhat is the [accuracy of the physical examination] to [identify skull fractures] in [pediatric patients presenting to the ED]? Clinical ScenarioA 5-year-old female presents to the emergency department after a fall from playground equipment. Parents are concerned about significant head injury. You perform history and physical exam and would like to use a pediatric head injury algorithm to help guide your need for advanced imaging and you hope to avoid unneeded imaging.
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Feb 1, 2024 | 
nature.com | Jeffrey Jones |Fred Gage
AbstractSchizophrenia (SZ) is a serious mental illness and neuropsychiatric brain disorder with behavioral symptoms that include hallucinations, delusions, disorganized behavior, and cognitive impairment. Regulation of such behaviors requires utilization of neurotransmitters released to mediate cell-cell communication which are essential to brain functions in health and disease. We hypothesized that SZ may involve dysregulation of neurotransmitters secreted from neurons.
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Nov 21, 2023 | 
frontiersin.org | Abed AlFatah Mansour |Yanhong Shi |Jeffrey Jones
IntroductionAstrocytes are abundant cells in the central nervous system (CNS) that serve myriad functions in maintaining the general homeostasis of neurons during healthy development, maturation, and aging.
