Jenny Rao

Jan 2, 2025 | jci.org | Bryan Wang |Seong Won Kim |Lori Luo |Xiaokan Zhang |Rajesh Kumar Soni |Roberta Lock | +11 more

AbstractLoss of Bcl2-associated athanogene 3 (BAG3) is associated with dilated cardiomyopathy (DCM). BAG3 regulates sarcomere protein turnover in cardiomyocytes; however, the function of BAG3 in other cardiac cell types is understudied. In this study, we used an isogenic pair of BAG3-knockout and wild-type human induced pluripotent stem cells (hiPSCs) to interrogate the role of BAG3 in hiPSC-derived cardiac fibroblasts (CFs).

Mar 14, 2023 | cell.com | Bryan Wang |Trevor Nash |Xiaokan Zhang |Jenny Rao

Muchtar E. Blauwet L.A. Gertz M.A. Restrictive cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy. Circ. Res. 2017; 121: 819-837https://doi.org/10.1161/CIRCRESAHA.117.310982Felker G.M. Thompson R.E. Hare J.M. Hruban R.H. Clemetson D.E. Howard D.L. Baughman K.L. Kasper E.K. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N. Engl. J. Med.