Jerry Lo

Oct 18, 2023 | biorxiv.org | Shimrit Avraham |Ben Korin |Jerry Lo |Mayra Cruz Tleugabulova

AbstractRecent evidence suggests that the interaction between the tumor microenvironment (TME) and systemic host environment can alter the host immune system to promote anti-tumor activity. Here, we investigated whether glomerular immune injury affects cancer progression. We used nephrotoxic serum nephritis (NTN), a model for glomerular immune injury, and followed it by cancer cell implantation. NTS-injected mice developed smaller primary tumors compared with controls.