Mayra Cruz Tleugabulova

Nov 6, 2024 | nature.com | Mayra Cruz Tleugabulova |Sandra P. Melo |Meizi Liu |Antonie Lechner |Basak Corak |Jonathan J. Hodgins | +5 more

AbstractMacrophages are pleiotropic and diverse cells that populate all tissues of the body. Besides tissue-specific resident macrophages such as alveolar macrophages, Kupffer cells, and microglia, multiple organs harbor at least two subtypes of other resident macrophages at steady state. During certain circumstances, like tissue insult, additional subtypes of macrophages are recruited to the tissue from the monocyte pool.

Oct 18, 2023 | biorxiv.org | Shimrit Avraham |Ben Korin |Jerry Lo |Mayra Cruz Tleugabulova

AbstractRecent evidence suggests that the interaction between the tumor microenvironment (TME) and systemic host environment can alter the host immune system to promote anti-tumor activity. Here, we investigated whether glomerular immune injury affects cancer progression. We used nephrotoxic serum nephritis (NTN), a model for glomerular immune injury, and followed it by cancer cell implantation. NTS-injected mice developed smaller primary tumors compared with controls.