Jessica Davidson

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Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV

3 weeks ago | cell.com | Jessica Davidson |Raghav Jain |Thomas Kizzar |Gisela Geoghegan |Daniel Nesbitt |Amy Cavanagh | +20 more

Keywordslysosomelipidomicslivercold exposureliquid chromatography-mass spectrometryLC-MStranscription factor EBTFEBphospholipase A2 G15Pla2g15bis(monoacylglycero)phosphateBMPIntroductionThe liver maintains energy homeostasis in mammals by acting as a metabolic transistor switching between providing glucose or lipids for peripheral tissue catabolism. In the fed state, the liver is a sink for excess glucose to maintain normoglycemia.

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