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2 months ago | 
mdpi.com | Yan Gao |Dandan Wang |Qian Wang |Jinfeng Wang
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Dec 31, 2024 | 
mdpi.com | Qian Wang
4. Experimental Results and AnalysisThis section first examines the effectiveness of two improvement strategies integrated into HERIME. Then, the performance of HERIME is analyzed and compared with several classical advanced algorithms together with some high-performance improved algorithms. 4.1. Experimental Setup and Evaluation CriteriaAll experiments were conducted on a CPU with properties of AMD R9 7950X @ 5.20 GHz, 64 GB RAM, running on the Windows 10 operating system.
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Dec 28, 2024 | 
arthritis-research.biomedcentral.com | Yupei Zhang |Nan Jiang |Xinwang Duan |Jian Xu |Lijun Wu |Wei Wei | +9 more
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Dec 17, 2024 | 00840-7?rss=yes&sz=64)
cell.com | Yiming Shi |Jiaming Zhang |Xingyi Li |Yuchong Han |Jiangheng Guan |Yilin Li | +14 more
Keywordsintrinsically photosensitive retinal ganglion cellsorientation selectivityprimary visual cortexvisual discriminabilityGet full text accessLog in, subscribe or purchase for full access. References1. Chang, L. ∙ Tsao, D.Y.The Code for Facial Identity in the Primate BrainCell. 2017; 169:1013-1020.e142. Simoncelli, E.P. ∙ Olshausen, B.A.Natural image statistics and neural representationAnnu. Rev. Neurosci. 2001; 24:1193-12163.
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Dec 5, 2024 | 
biorxiv.org | Qian Wang |Yicheng Guo |Ryan G. Casner |Jian Yu
AbstractSARS-CoV-2 has largely evolved to resist antibody pressure, with each successive viral variant becoming more and more resistant to serum antibodies in the population. This evolution has rendered inactive all therapeutic monoclonal antibodies previously authorized, and it is now threatening the remaining clinical product for immunoprophylaxis against COVID-19.
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Nov 7, 2024 | 
nature.com | Qian Wang
AbstractThe pharmacokinetics of vancomycin exhibit significant inter-individual variability, particularly among elderly patients. This study aims to develop a predictive model that integrates machine learning with population pharmacokinetics (popPK) to facilitate personalized medication management for this demographic. A retrospective analysis incorporating 33 features, including popPK parameters such as clearance and volume of distribution.
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Nov 4, 2024 | 
dialnet.unirioja.es | Qian Wang
Ayuda Buscar en la ayuda Buscar en la ayuda Against the Implied Translator Autores: Qian Wang Localización: Translation and literature, ISSN 0968-1361, Vol. 33, Nº. 1, 2024, págs.
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Oct 28, 2024 | 
nature.com | Hang Zhang |Qian Wang
AbstractSecreted CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide ligands dimension the stem cell niche of Arabidopsis shoot meristems by signalling through redundant and cross-compensating CLAVATA1 (CLV1)-type receptor kinases. In the root meristem, the CLV1 homologues BARELY ANY MERISTEM 1 (BAM1) and BAM2 drive CLE13/16-mediated formative divisions that produce the ground tissue layers.
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Oct 27, 2024 | 
biorxiv.org | Zhiqing Zhang |Saumya Anang |Qian Wang |Hanh Nguyen
AbstractDuring human immunodeficiency virus (HIV-1) entry into host cells, binding to the receptors, CD4 and CCR5/CXCR4, triggers conformational changes in the metastable envelope glycoprotein (Env) trimer ((gp120-gp41)3). CD4 binding induces Env to make transitions from its pretriggered conformation (PTC) to more "open" conformations that are sensitive to inhibition by antibodies, CD4-mimetic compounds (CD4mcs) and exposure to cold.
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Oct 23, 2024 | 
pubs.rsc.org | Dan Luo |Qian Wang |Jiang Liu |Haibo Mei
Electrochemical synthesis of γ-carbolinones via sulfonylation-triggered cyclization of indole-3-carboxamides
A novel electrochemical radical cyclization reaction of N-acryloyl-indole-3-carboxamides with sodium sulfinates as coupling partners has been developed, which delivers multi-substituted γ-carbolinones as products with up to 70% yields. This study represents the first example of the radical cyclization reaction of indole-3-carboxamides under electrochemical conditions.
