Jian Zeng

Jun 16, 2024 | medrxiv.org | Junhao Wen |Jian Zeng |Li Shen |Andrew Zalesky

The authors have declared no competing interest. NAI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. YesThe details of the IRB/oversight body that provided approval or exemption for the research described are given below:We only used GWAS summary statistics, not individual data, from UK Biobank, FinnGen, and PGC. Therefore, they are all publicly available.

Jun 14, 2024 | nature.com | Jian Zeng

Correction to: Scientific Reports https://doi.org/10.1038/s41598-024-63949-1, published online 07 June 2024The original version of this Article contained errors.

Mar 12, 2024 | nature.com | Angli Xue |Zhihong Zhu |Huanwei Wang |Peter M. Visscher |Jian Zeng

AbstractSubstance use behaviours (SUB) including smoking, alcohol consumption, and coffee intake are associated with many health outcomes. However, whether the health effects of SUB are causal remains controversial, especially for alcohol consumption and coffee intake. In this study, we assess 11 commonly used Mendelian Randomization (MR) methods by simulation and apply them to investigate the causal relationship between 7 SUB traits and health outcomes.