Jiangning Song

2 weeks ago | nature.com | Yiwen Zhang |Rongbin Xu |Wenzhong Huang |Tingting Ye |Pei Yu |Wenhua Yu | +18 more

AbstractUnder a warming climate, wildfires are becoming more frequent and severe. Multicountry studies evaluating associations between wildfire fine particulate matter (PM2.5) and respiratory hospitalizations are lacking. Here we evaluate the short-term effects of wildfire-specific PM2.5 on respiratory hospitalizations from 1,052 communities across Australia, Brazil, Canada, Chile, New Zealand, Vietnam, Thailand and Taiwan, during 2000–2019.

Oct 26, 2023 | biorxiv.org | Hoai-An Nguyen |Anton Y. Peleg |Jiangning Song |Bhavna Antony

AbstractMatrix–assisted laser desorption/ionization–time of flight mass spectrometry (MALDI–TOF MS) is widely used in clinical microbiology laboratories for bacterial identification but its use for prediction of antimicrobial resistance (AMR) remains limited. Here, we used MALDI–TOF MS with artificial intelligence (AI) approaches to successfully predict AMR in Pseudomonas aeruginosa, a priority pathogen with complex AMR mechanisms.

Oct 19, 2023 | nature.com | Jiangning Song |Robin B Gasser |Ruedi Aebersold |Guohua Wang

AbstractCell type deconvolution is a computational method for the determination/resolution of cell type proportions from bulk sequencing data, and is frequently used for the analysis of divergent cell types in tumour tissue samples. However, deconvolution technology is still in its infancy for the analysis of cell types using proteomic data due to challenges with repeatability/reproducibility, variable reference standards and the lack of single-cell proteomic reference data.