Ruedi Aebersold

Nov 12, 2023 | theanalyticalscientist.com | Ruedi Aebersold

In recent years, the impact of analytical science in the life sciences has been particularly impressive. Advanced fluorescent imaging techniques were the basis for sequencing the genome, cryoEM single-particle analysis revealed the structure of biomolecules at atomic resolution, and mass spectrometric techniques have made great inroads towards the exploration of the many layers of information of the proteome.

Oct 19, 2023 | nature.com | Jiangning Song |Robin B Gasser |Ruedi Aebersold |Guohua Wang

AbstractCell type deconvolution is a computational method for the determination/resolution of cell type proportions from bulk sequencing data, and is frequently used for the analysis of divergent cell types in tumour tissue samples. However, deconvolution technology is still in its infancy for the analysis of cell types using proteomic data due to challenges with repeatability/reproducibility, variable reference standards and the lack of single-cell proteomic reference data.

Mar 2, 2023 | nature.com | Laurent Gatto |Ruedi Aebersold |Juergen Cox |Vadim Demichev |Jason Derks |Edward Emmott | +7 more

The goal of reporting is to enable other researchers to repeat, reproduce, assess and build upon published data and their interpretation79. While reproduction and replication do not guarantee accuracy, they build trust in the analysis process through verifiability, thus strengthening confidence in the reported data and results.