Jinmiao Chen

Dec 3, 2024 | biorxiv.org | Xuhua Yan |Jinmiao Chen |Ruiqing Zheng

AbstractThe integration of single-cell multi-omics datasets is critical for deciphering cellular heterogeneities. Mosaic integration, the most general integration task, poses a greater challenge regarding disparity in modality abundance across datasets. Here, we present ACE, a mosaic integration framework that assembles two types of strategies to handle this problem: modality-alignment based strategy (ACE-align) and regression-based strategy (ACE-spec).

Oct 15, 2024 | nature.com | Jinmiao Chen

AbstractSpatial transcriptomics produces high-dimensional gene expression measurements with spatial context. Obtaining a biologically meaningful low-dimensional representation of such data is crucial for effective interpretation and downstream analysis.

Oct 14, 2024 | flipboard.com | Kok Siong Ang |Jinmiao Chen |Chengwei Zhong

3 hours agoBut there is something you can do about it, according to the experts. Many people consider eyebrows to be a frame for the face, but ... wait, did my frame just fall off the wall? If you’re suddenly getting much more familiar— and heavy-handed — with your eyebrow pencil, it might be because your …