Johannes Buchner

Aug 29, 2024 | aanda.org | Johannes Buchner

Home All issues Volume 689 (September 2024) A&A, 689 (2024) L2 Full HTML Issue A&A Volume 689, September 2024 Article Number L2 Number of page(s) 5 Section Letters to the Editor DOI https://doi.org/10.1051/0004-6361/202451170 Published online 30 August 2024 A&A, 689, L2 (2024) Letter to the Editor Impediments to the cosmic growth of galaxies: The outflow budget from Star Formation and Active Galactic Nuclei ,⋆ Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, 85741...

May 3, 2024 | jbc.org | Andreas Maier |Johannes Buchner

AbstractPosttranslational modifications of Hsp90 are known to regulate its in-vivo chaperone functions. Here we demonstrate that the lysine acetylation-deacetylation dynamics of Hsp82 is a major determinant in DNA repair mediated by Rad51. We uncover that the deacetylated lysine 27 in Hsp82 dictates the formation of the Hsp82-Aha1-Rad51 complex, which is crucial for client maturation.

Apr 12, 2024 | onlinelibrary.wiley.com | Johannes Buchner |Hristo L. Svilenov |Johanna Trommer |Florian Lesniowski

1 INTRODUCTION In most mammalian antibodies, the complementarity-determining regions (CDRs) from both the heavy chain (HC) and the light chain (LC) form the antigen-binding site. There are only a few exceptions to this paradigm such as the HC-only antibodies in camelids (Hamers-Casterman et al., 1993) and the antibodies with ultra-long CDR-H3s in cattle (Wang et al., 2013).

Jan 25, 2021 | nature.com | Johannes Buchner

Aug 25, 2020 | cell.com | Johannes Buchner