John M. Koomen

Feb 7, 2024 | nature.com | Bin Fang |Michael White |John M. Koomen |Jennifer Wargo |Jianfei Qi

AbstractMelanoma incidence and mortality rates are historically higher for men than women. Although emerging studies have highlighted tumorigenic roles for the male sex hormone androgen and its receptor (AR) in melanoma, cellular and molecular mechanisms underlying these sex-associated discrepancies are poorly defined.