John Suckling

1 month ago | biologicalpsychiatryjournal.com | Kelly Byrne |Fabio Sambataro |John Suckling

Elevated pro-inflammatory markers have been reported in schizophrenia, and inflammation has been found to modulate functional connectivity (FC). Here, we investigated striatal connectivity associated with inflammation in first-episode schizophrenia (FES) and its association with negative symptoms and cognitive performance.

Sep 11, 2024 | nature.com | Jakob Seidlitz |Golia Shafiei |Kate Merritt |Anthony David |Sarah Morgan |Rosa Ayesa-Arriola | +6 more

AbstractThe psychosis spectrum encompasses a heterogeneous range of clinical conditions associated with abnormal brain development. Detecting patterns of atypical neuroanatomical maturation across psychiatric disorders requires an interpretable metric standardized by age-, sex- and site-effect. The molecular and micro-architectural attributes that account for these deviations in brain structure from typical neurodevelopment are still unknown.