Kate Merritt

Sep 11, 2024 | nature.com | Jakob Seidlitz |Golia Shafiei |Kate Merritt |Anthony David |Sarah Morgan |Rosa Ayesa-Arriola | +6 more

AbstractThe psychosis spectrum encompasses a heterogeneous range of clinical conditions associated with abnormal brain development. Detecting patterns of atypical neuroanatomical maturation across psychiatric disorders requires an interpretable metric standardized by age-, sex- and site-effect. The molecular and micro-architectural attributes that account for these deviations in brain structure from typical neurodevelopment are still unknown.

Feb 2, 2024 | biologicalpsychiatryjournal.com | Kate Merritt |Robert McCutcheon |Sarah Ashley |Anthony David

Glutamatergic dysfunction is implicated in schizophrenia pathoaetiology, but this may vary in extent between patients. We examine whether patients exhibit greater variability in glutamate measures compared to controls and conduct an updated meta-analysis of glutamate differences.