Joonas Naamanka

Jul 18, 2023 | nature.com | Thomas D. Als |Jakob Grove |Georgios Voloudakis |Karen Therrien |Joonas Naamanka |Daniel F Levey | +15 more

AbstractDepression is a common psychiatric disorder and a leading cause of disability worldwide. Here we conducted a genome-wide association study meta-analysis of six datasets, including >1.3 million individuals (371,184 with depression) and identified 243 risk loci. Overall, 64 loci were new, including genes encoding glutamate and GABA receptors, which are targets for antidepressant drugs.