Jun S. Lai

Nov 28, 2024 | cell.com | Milica Moskovljevic |Filippo Dragoni |Nathan L. Board |Fengting Wu |Jun S. Lai |Hao Zhang | +10 more

Keywords HIV-1 persistence HIV-1 latent reservoir latency reversal antigenic stimulation dendritic cells CD4+ T cells cytomegalovirus Introduction Antiretroviral therapy (ART) effectively blocks viral replication, but HIV-1 persists in a small pool of latently infected resting CD4+ T cells harboring inducible, replication-competent proviruses.1,2,3 This reservoir was originally characterized with a quantitative viral outgrowth assay (QVOA) in which resting CD4+ T cells are stimulated with...

Oct 18, 2023 | mdpi.com | Jun S. Lai |Keith Godfrey |Choon Nam Ong |Kok Hian Tan

3. Results 3.1. Study Sample CharacteristicsTable 1 presents the demographic, lifestyle, and clinical characteristics along with the average concentrations of individual carotenoids and E vitamers for the 678 women included. The women were, on average, 31 years old at delivery. Most were of Chinese ethnicity (59%), had attained tertiary education (37.4%), were multiparous (56.2%) at recruitment, and did not engage in moderate–vigorous physical activity (70%).

Apr 13, 2023 | mdpi.com | Marjorelee Colega |Keith Godfrey |Kok Hian Tan |Jun S. Lai

1. IntroductionThere is evidence that adopting a healthy diet during pregnancy is associated with better pregnancy outcomes such as lower risks of gestational diabetes [1] and preterm birth [2], as well as better offspring metabolic and cognitive health [3,4]. Having a healthy diet after pregnancy is also important to ensure optimal maternal health in the long term.