Kai Luo

Nov 11, 2024 | onlinelibrary.wiley.com | Yiling Li |Mingyue Wang |Ping Chen |Kai Luo

Conflicts of Interest The authors declare no conflicts of interest. Supporting Information References W. W. Adams Iii, and I. Terashima, ed. 2018. The Leaf: A Platform for Performing Photosynthesis. Cham: Springer International Publishing. , and . 1990. “Developmental Regulation of Enzymes of Sucrose and Hexose Metabolism in Effective and Ineffective Soybean Nodules.” Plant Physiology 92: 346–351. 1986.

Sep 17, 2024 | nature.com | Kai Luo |Yanbo Zhang

replying to M. G. Kakkoura et al. Nature Metabolism https://doi.org/10.1038/s42255-024-01128-2 (2024)We thank Kakkoura and colleagues1 for their commentary on our recent study, which reported an inverse association between milk intake and incident type 2 diabetes (T2D) in lactase non-persistent (LNP) individuals with a potential mediating role of gut microbiota and related metabolites2.

Jun 13, 2024 | chembioagro.springeropen.com | Bingyu Wang |Junyi Li |Kai Luo |Honggang Wang |Yu Gao |Yixuan Wang | +4 more

Glyphosate, widely used to manage weeds in cassava crops, simultaneously inhibits cassava growth, necessitating the development of herbicide-tolerant cassava varieties. In this study, screened 262 cassava varieties, identifying the glyphosate-resistant (GR) variety ZM8701 and the glyphosate-sensitive (GS) variety SC9. Transcriptomic analysis via Illumina sequencing revealed differentially expressed genes associated with resistance, including Cytochrome P450, GST, GT, ABC transporters, and others such as MIOX1, LHCA1, PPH, HSP26, HSP83A, and UGT73C5. Notably, the EMB3004 gene, involved in the biosynthesis of aromatic amino acids, was significantly upregulated in resistant varieties, suggesting a key role in countering glyphosate’s inhibition of the shikimic acid pathway. These genes are pivotal in enhancing cell wall biosynthesis, optimizing photosynthesis, and improving detoxification processes. This research elucidated the molecular mechanisms underlying cassava’s resistance to glyphosate, thereby laying the groundwork for breeding programs aimed at developing herbicide-resistant varieties.

Apr 18, 2024 | bmccancer.biomedcentral.com | Ke Zong |Kai Luo |Hongfei Wang |Jianfei Hu |Shi Chen |Renfeng Li | +2 more

The RNA sequences of 422 patients (50 normal tissues and 374 tumor tissues) were extracted from the TCGA-HCC database, and the RNA sequences of 445 patients (202 normal tissues and 243 tumor tissues) were extracted from the ICGC-LIRI-JP database. Ferroptosis-related genes were acquired from FerrDb, an online source that supplies a comprehensive and updated checklist of ferroptosis markers, regulative molecules, and ferroptosis-disease associations [12].