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1 month ago | 
jci.org | Svenja Weiss |Hung-Mo Lin |Eric Acosta |Natalia L. Komarova |Ping Chen |Dominik Wodarz | +10 more
AbstractEarly antibody therapy can prevent severe SARS-CoV-2 infection (COVID-19). However, the effectiveness of COVID-19 convalescent plasma (CCP) therapy in treating severe COVID-19 remains inconclusive. To test a hypothesis that some CCP units are associated with a coagulopathy hazard in severe disease that offsets its benefits, we tracked 304 CCP units administered to 414 hospitalized COVID-19 patients to assess their association with the onset of unfavorable post-transfusion D-dimer trends.
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2 months ago | 00058-3?rss=yes&sz=64)
cell.com | Cynthia Palmer |Britton Boras |Scott Garza |Jing Yuan |Tae Sung |Elizabeth McMillan | +45 more
KeywordsatirmociclibPF-07220060CDK4cyclin D1breast cancercell cyclecell cycle inhibitorneutropeniacyclin-dependent kinaseCDK6IntroductionAberrant cell proliferation is a fundamental hallmark of human cancer.1 In tumor cells, it is frequently orchestrated by cyclin D-dependent kinases, CDK4 and CDK6; each kinase forms active complexes with one of the three D-type cyclins (D1, D2, or D3).
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Dec 20, 2024 | 
mdpi.com | Ping Chen
1. IntroductionWith the rapid development of the Internet of Things (IoT), smart wearable devices are playing a crucial role in advancing human–machine interaction [1], personalized healthcare [2], and anti-counterfeiting applications [3,4].
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Dec 4, 2024 | 
pubs.acs.org | Yachen Wang |Feng Liang |Jing Yang |Ping Chen
IntroductionClick to copy section linkSection link copied!GaN-based blue and green laser diodes (LDs) have been extensively studied and developed, primarily driven by their significant applications in laser display, solid-state lighting, underwater communication, and other fields. (1−4) Among them, GaN-based VCSELs have garnered significant attention in recent years due to the pursuit of excellent performance characteristics of lasers such as single-mode operation and low-divergence angles.
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Dec 4, 2024 | 
dx.doi.org | Yachen Wang |Feng Liang |Jing Yang |Ping Chen
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Nov 11, 2024 | 
onlinelibrary.wiley.com | Yiling Li |Mingyue Wang |Ping Chen |Kai Luo
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information References W. W. Adams Iii, and I. Terashima, ed. 2018. The Leaf: A Platform for Performing Photosynthesis. Cham: Springer International Publishing. , and . 1990. “Developmental Regulation of Enzymes of Sucrose and Hexose Metabolism in Effective and Ineffective Soybean Nodules.” Plant Physiology 92: 346–351. 1986.
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Oct 17, 2024 | 
pubs.rsc.org | Xiao-Li Tian |Ping Chen |Yue Hu |Lan Zhang
Enhanced gene transfection ability of sulfonylated low molecular weight PEI and its application in anti-tumor treatment
With the continuous progress of nanotechnology in the field of tumor vaccines, immunotherapy has been regarded as one of the most powerful approaches for cancer treatment. Currently, DNA vaccines were used to efficiently deliver the plasmid encoding tumor associated antigen to antigen-presenting cells (APCs) and enhance the activation of immune cells.
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Oct 10, 2024 | 
analyticalsciencejournals.onlinelibrary.wiley.com | Qin Chen |Ping Chen |Xue Shen |Chunmei Bi
CONFLICT OF INTEREST STATEMENT The authors declare that there were not known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Supporting Information Filename Description bmc6015-sup-0001-Supporting_Information.docxWord 2007 document , 634.1 KB Figure S1. Schematic flow of the extraction procedure. Figure S2. (A) The fingerprint based UHPLC-QTOF-MS of 34 samples of ARE.
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Sep 27, 2024 | 
mdpi.com | Yang Yu |Tian Li |Ping Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Sep 9, 2024 | 
jnis.bmj.com | Pan Zhang |Ping Chen |Yingjie Xu |Miaomiao Hu
AbstractBackground The clinical relevance of differentiating between mTICI (modified Thrombolysis In Cerebral Infarction) 2b and mTICI 3 in patients with vertebrobasilar artery occlusion (VBAO) remains unclear. This study aimed to investigate whether mTICI 3 improves functional outcomes compared with mTICI 2b in patients with VBAO and whether this improvement differs according to extent of ischemic damage.
