Kathryn E Kemper

Oct 7, 2024 | nature.com | Julia Sidorenko |Kathryn E Kemper |Bjørn Olav Åsvold |Alireza Ani |Rujia Wang |Ilja M. Nolte | +13 more

AbstractLinkage studies have successfully mapped loci underlying monogenic disorders, but mostly failed when applied to common diseases. Conversely, genome-wide association studies (GWASs) have identified replicable associations between thousands of SNPs and complex traits, yet capture less than half of the total heritability.