Kathy K. Niakan

Jan 8, 2025 | cell.com | Georgia Lea |Paula Doria-Borrell |Ana Ferrero-Micó |Anakha Varma |Claire Simon |Holly Anderson | +8 more

IntroductionThe isolation and culture of human embryonic stem cells (hESCs) has been invaluable in building our understanding of pluripotency, cell fate commitment, differentiation, epigenetic programming, and gene regulation in human development.1,2 The derivation of the analogous cells for the human placental lineage has taken longer to develop and hence these processes in trophoblast remain less well understood.

Jul 4, 2024 | progress.org.uk | Sandy Starr |Roger Sturmey |Kathy K. Niakan

PET and Cambridge Reproduction have jointly published a new Code of Practice for the Generation and Use of Human Stem Cell-Based Embryo Models (the SCBEM Code of Practice), in order to support the development of best practice in research involving stem-cell-based embryo models (SCBEMs). The Working Group that has drafted the SCBEM Code of Practice is composed of researchers and practitioners at institutions across the UK, including experts in science, law, ethics and regulation.