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Nov 21, 2024 | 
digitalcommons.library.tmc.edu | Elaine Stur |Sara Corvigno |Mingchu Xu |Ken Chen
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Nov 20, 2024 | 
msn.com | Ken Chen
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Nov 20, 2024 | 
phys.org | Ken Chen
Stars with masses between 10 and 30 times that of the sun, in their final evolutionary stages, form an iron core that ultimately collapses into a neutron star. This collapse releases a tremendous amount of gravitational potential energy through neutrinos, triggering a shockwave that destroys the entire star.
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Nov 5, 2024 | 
biorxiv.org | Dawei Dai |Ken Chen |Jingwen Tao |Ben Williams
AbstractHow organisms age is a question with broad implications for human health. In mammals, DNA methylation is a biomarker for biological age, which may predict age more accurately than date of birth. However, limitations in mammalian models make it difficult to identify mechanisms underpinning age-related DNA methylation changes.
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Oct 30, 2024 | 
nature.com | Mirazul Islam |Yilin Yang |Alan Simmons |Naila Tasneem |Zhengyi Chen |Iannish D. Sadien | +9 more
AbstractTemporal ordering of cellular events offers fundamental insights into biological phenomena. Although this is traditionally achieved through continuous direct observations1,2, an alternative solution leverages irreversible genetic changes, such as naturally occurring mutations, to create indelible marks that enables retrospective temporal ordering3,4,5.
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Oct 24, 2024 | 
medrxiv.org | Ken Chen |Ying Zhao |Zheng Wei |Ying Yu
The authors have declared no competing interest. The present study is a Mendelian Randomization study, thus we did not have a clinical trial ID. No external funding was received. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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Sep 11, 2024 | 
mdpi.com | Zisheng Li |Ken Chen |Yaoqin Xie
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Aug 21, 2024 | 
airliners.net | Wang Wenxuan |Ken Chen
Distinct Views: 11 Photo Added: August 22, 2024 Photo Copyright © Wang Wenxuan. All rights reserved. Airliners.net is not affiliated with any entity mentioned or pictured herein. All trademarks are the property of their respective owners.
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Jul 30, 2024 | 
nature.com | Sarina Piha-Paul |Vivek Subbiah |Aung Naing |Jaffer Ajani |Kanwal Raghav |Gordon Mills | +3 more
AbstractCancer cells with BRCA1/2 deficiencies are sensitive to poly (ADP-ribose) polymerase (PARP) inhibitors. We evaluated the efficacy of talazoparib in DNA-Damage Repair (DDR)-altered patients. In this phase II trial, patients were enrolled onto one of four cohorts based on molecular alterations: (1) somatic BRCA1/2, (2) other homologous recombination repair pathway, (3) PTEN and (4) germline BRCA1/2.
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Jul 10, 2024 | 
onlinelibrary.wiley.com | Bin Lyu |Materials Engineering Shaanxi |Ken Chen |Jiamin Zhu
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202402510-sup-0001-SuppMat.docx24.8 MB Supporting Information References 1, , , Acc. Chem. Res. 2021, 54, 4051. 2, , , , Adv. Sci. 2022, 9, 2203856. 3, , , , J. Cleaner Prod. 2019, 208, 1524. 4, , , , , , Nat Rev Earth Environ 2020, 1, 189. 5, , , , , , , , Adv. Funct. Mater. 2023, 33, 2307301. 6, , , , , , J. Mater. Sci. Technol. 2022, 97, 190.
