Kristen J. Brennand

Dec 4, 2024 | nature.com | Michael Breen |Laura M Huckins |Daniel Paull |Kristen J. Brennand

Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-022-01161-y, published online 20 October 2022. In the version of the article initially published, Saunil Dobariya (The New York Stem Cell Foundation Research Institute, New York, NY, USA) was missing from the author list and is now included in the HTML and PDF versions of the article.

Jun 1, 2024 | ajp.psychiatryonline.org | Kristen J. Brennand

Ever since the seminal report of human induced pluripotent stem cells (hiPSCs) in 2007 (1), and from it the implication that patient-specific cells of any type could be differentiated for models of development and disease, the pressing question has been “How closely do stem cell–derived cells recapitulate those in the original donor?” Particularly given that cellular reprogramming erases epigenetic, transcriptomic, and even morphological markers of age in hiPSCs and their differentiated...

Mar 1, 2024 | cell.com | Laura M Huckins |Kristen J. Brennand |Cynthia Bulik

HighlightsFeeding and eating disorders (FEDs) are common and have been shown to be influenced by both genetic and environmental factors. Avoidant/restrictive food intake disorder, anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED) are all heritable and genome-wide association studies (GWASs) reveal both psychiatric and metabolic/anthropometric genetic risk factors for AN. GWASs for other FEDs are underway.