Laura M Huckins

Dec 4, 2024 | nature.com | Michael Breen |Laura M Huckins |Daniel Paull |Kristen J. Brennand

Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-022-01161-y, published online 20 October 2022. In the version of the article initially published, Saunil Dobariya (The New York Stem Cell Foundation Research Institute, New York, NY, USA) was missing from the author list and is now included in the HTML and PDF versions of the article.

Aug 28, 2024 | psiquiatria.com | Laura M Huckins |Rebecca Signer

En los últimos años, se han logrado avances significativos en la comprensión de la genética de la anorexia nerviosa (AN) y otros trastornos alimentarios (TA). Estos progresos han sido posibles gracias a los esfuerzos de consorcios colaborativos a gran escala, que han identificado los primeros loci significativos a nivel genómico y genes asociados con la AN. Además, se han obtenido conocimientos valiosos sobre las bases metabopsiquiátricas que subyacen a estos trastornos.

Mar 1, 2024 | cell.com | Laura M Huckins |Kristen J. Brennand |Cynthia Bulik

HighlightsFeeding and eating disorders (FEDs) are common and have been shown to be influenced by both genetic and environmental factors. Avoidant/restrictive food intake disorder, anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED) are all heritable and genome-wide association studies (GWASs) reveal both psychiatric and metabolic/anthropometric genetic risk factors for AN. GWASs for other FEDs are underway.

Feb 20, 2024 | nature.com | Andrew Morris |George Smith |Laura M Huckins

AbstractMultimorbidity represents an increasingly important public health challenge with far-reaching implications for health management and policy. Mental health and metabolic diseases have a well-established epidemiological association. In this study, we investigate the genetic intersection between type 2 diabetes and schizophrenia. We use Mendelian randomization to examine potential causal relationships between the two conditions and related endophenotypes.

Dec 7, 2023 | nature.com | Hang Zhou |Rachel L. Kember |Joseph D. Deak |Travis T. Mallard |Jiayi Xu |Emma Johnson | +18 more

AbstractProblematic alcohol use (PAU), a trait that combines alcohol use disorder and alcohol-related problems assessed with a questionnaire, is a leading cause of death and morbidity worldwide. Here we conducted a large cross-ancestry meta-analysis of PAU in 1,079,947 individuals (European, N = 903,147; African, N = 122,571; Latin American, N = 38,962; East Asian, N = 13,551; and South Asian, N = 1,716 ancestries).