Kunal Shah

3 weeks ago | digitalcommons.library.tmc.edu | Kunal Shah

AbstractIntracellular Ca2+ signaling via changes or oscillation in cytosolic Ca2+ concentration controls almost every aspect of cellular function and physiological processes, such as gene transcription, cell motility and proliferation, muscle contraction, and learning and memory. Two-pore channels (TPCs) are a class of eukaryotic cation channels involved in intracellular Ca2+ signaling, likely present in a multitude of organisms from unicellular organisms to mammals.

1 month ago | dev.to | Kunal Shah

Why We Chose Shopaccino as Our eCommerce EngineWe evaluated several platforms (Shopify Plus, WooCommerce with B2B plugins, and Magento), but chose Shopaccino for three primary reasons:Built-in B2B features like bulk pricing, GST management, and dealer-specific login. Flexible category-level control and filtering that suited our product structure. Localized support with experience in Indian commerce logistics.

1 month ago | producthunt.com | Kunal Shah |Rashid Hussain

HomeProductDazzleCreate Ads super fast from an image uploadDazzle allows you to create ads instantly from your product image and brand guidelines. Just drag over a product image, choose a backdrop from our intelligently-curated suggestions, and watch your pixel-perfect ads come to life. Free OptionsLaunch tags:Design Tools•Marketing•AdvertisingAbout this launchDazzleCreate Ads at Light Speedwas hunted by in Dazzle by Design Tools, Marketing, Advertising. Made by and . Featured on May 1st, 2025.

Feb 8, 2025 | biorxiv.org | Kunal Shah |Paul Kennedy |James Black |Kevin Litchfield

AbstractLIMD1 is a tumour suppressor gene frequently lost in non-small cell lung cancer (NSCLC), but its role in cancer-immune cell interactions remains unexplored. Here, we demonstrate that LIMD1 loss results in upregulation of the key immune checkpoint protein PD-L1. Using multi-region sequencing from the TRACERx dataset, we identify that LIMD1 loss is clonal in over 80% of squamous cell carcinoma (LUSC) and 40% of lung adenocarcinoma (LUAD) cases, correlating with increased PD-L1 expression.

Dec 11, 2024 | dev.to | Kunal Shah

Secure AWS VPC using Public and Private SubnetsProject Overview —In this lab, you will gain hands-on experience creating and configuring a Virtual Private Cloud (VPC) using the AWS Management Console. The project will culminate in the deployment of a common two-tiered cloud architecture, including front-end and back-end components. Solutions Architecture —Prerequisite —AWS Account with Admin Access.