L. Bryan Ray

1 week ago | science.org | Corinne N. Simonti |Jesse R. Smith |L. Bryan Ray |Madeleine Seale

Metabolism Artificial sweetener link to vascular diseaseL. Bryan RayAspartame is a widely consumed artificial sweetener. Unfortunately, such sweeteners are linked to an increased risk of cardiovascular disease. Wu et al. explored how aspartame affected atherosclerosis in a mouse model lacking ApoE, a protein that functions in lipid metabolism. Consumption of aspartame made atherosclerotic symptoms worse.

3 weeks ago | science.org | Corinne N. Simonti |Jesse R. Smith |Stella Hurtley |L. Bryan Ray

Water Storage Poles on the moveJesse SmithThe Kariba dam on the Zambezi River has created the world’s largest artificial lake. PHOTO: IMPALA PHOTO/ISTOCK PHOTOHuman activities have been conducted at such immense scales that they literally have affected how the world turns. Valencic et al. discuss one dimension of that impact: movement of the poles due to water impoundment.

Jan 2, 2025 | science.org | Michael Funk |Jesse R. Smith |Phil Szuromi |Sacha Vignieri |Jake Yeston |Mattia Maroso | +8 more

Sep 5, 2024 | science.org | L. Bryan Ray |Jake Yeston |Michael Funk |Iyinoluwa Sofowora

Cell Cycle Choreographing centromere functionL. Bryan RayChromosomes, seen here in a transmission electron micrograph, have a central region known as the centromere that serves as an anchor for cytoskeletal proteins during mitosis. PHOTO: DR. KLAUS BOLLER / SCIENCE SOURCESuccessful cell division requires precise separation of chromosomes with near perfect fidelity to the daughter cells.

Jun 27, 2024 | science.org | Krishnan K Mahadevan |Dawid Zyla |L. Bryan Ray |Brent Grocholski

Biophysics Deep-sea membranes use the bendsL. Bryan RayDeep sea organisms such as the comb jelly Beroe cucumis, pictured here, produce phospholipids that aid in adaptation to extreme pressure. PHOTO: SEATOPS/ALAMY STOCK PHOTOOpen in viewerExtreme pressures thousands of feet deep in the ocean are sufficient to compress the conformation of the molecules that form biological membranes. Winnikoff et al. explored how comb jellies have adapted to such pressures.