Laura Cacciaguerra

Dec 31, 2024 | journals.sagepub.com | Laura Cacciaguerra |Loredana Storelli |Elisabetta Pagani |Paolo Preziosa

IntroductionAs demonstrated in aquaporin-4 (AQP4)-IgG positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), knowledge of the pathophysiology of autoimmune neurological conditions is the most important step for the development of tailored treatments.1,2Summarizing, a pro-inflammatory environment and the peripheral loss of self-tolerance lead to the production of autoreactive IgGs by plasmablasts.

Apr 9, 2024 | onlinelibrary.wiley.com | Vyanka Redenbaugh |James Fryer |Laura Cacciaguerra |John Chen

Introduction Myelin oligodendrocyte glycoprotein antibody (MOG-IgG) was identified as a biomarker of central nervous system (CNS) demyelinating disease in 2007.1 More recently, MOG-IgG-associated disease (MOGAD) was recognized as a separate disease, distinct from multiple sclerosis (MS) and aquaporin-4-IgG positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD) with international diagnostic criteria proposed in 2023.2 MOGAD is commonly associated with optic neuritis (ON), acute...

Sep 25, 2023 | n.neurology.org | Laura Cacciaguerra |Vyanka Redenbaugh |John Chen

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Jun 16, 2023 | n.neurology.org | Laura Cacciaguerra |Vyanka Redenbaugh |John Chen |Pearse Morris

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Mar 27, 2023 | n.neurology.org | Laura Cacciaguerra |Fort Sam Houston |Pearse Morris

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