Lauren Dawson

Feb 23, 2025 | nature.com | Lauren Dawson |Aashika Sekar |Alexander D Fulford |Rachel Lambert |Hannah Burgess

AbstractTissue growth is regulated by many signals, including polarity cues. The Hippo signalling pathway restricts tissue growth and receives inputs from the planar cell polarity-controlling Fat signalling pathway. The atypical cadherin Fat restricts growth via several mechanisms that ultimately control the activity of the pro-growth transcriptional co-activator Yorkie.

Feb 12, 2024 | biorxiv.org | Lauren Dawson |Alexander D Fulford |Aashika Sekar |Paulo Ribeiro

AbstractTissue growth is regulated by many signals, including polarity cues. The Hippo signalling pathway restricts tissue growth and receives inputs from the planar cell polarity-controlling Fat signalling pathway. The atypical cadherin Fat restricts growth via several mechanisms that ultimately control the activity of the pro-growth transcriptional co-activator Yorkie.

Jan 28, 2024 | biorxiv.org | Lauren Dawson |Paulo Ribeiro |Alexander D Fulford |Aashika Sekar

AbstractRegulation of tissue growth is influenced by many signals, including polarity cues. The Hippo signalling pathway restricts tissue growth and receives inputs from the planar cell polarity-controlling Fat signalling pathway. The atypical cadherin Fat restricts growth via several mechanisms that ultimately control the activity of the pro-growth transcriptional activator Yorkie.