Lauren Hodgson

May 7, 2024 | ophthalmologyscience.org | Himeesh Kumar |East Melbourne |Robyn Guymer |Lauren Hodgson

ABSTRACTTo understand the spatial relationship between local rod-mediated visual function and reticular pseudodrusen (RPD) in eyes with large drusen. Retrospective cross-sectional study. One eye with large drusen (>125μm) each from 91 individuals with intermediate age-related macular degeneration (AMD), with and without RPD.

Jan 29, 2024 | onlinelibrary.wiley.com | Zhichao Wu |Lauren Hodgson |Robyn Guymer |Jan H. Terheyden

1 INTRODUCTION A major challenge in the evaluation of new interventions to slow or prevent the development of late age-related macular degeneration (AMD) complications in its early stages is the need for large and lengthy trials given the slowly progressive nature of this disease.1, 2 Biomarkers that could be used to identify high-risk individuals to target in such trials, and/or act as earlier surrogate endpoints for progression to the conventional, gold-standard clinical endpoint of...

Nov 4, 2023 | ophthalmologyscience.org | East Melbourne |Emily Glover |Erin Gee |Lauren Hodgson

Complete retinal pigment epithelium (RPE) and outer retinal atrophy (cRORA) on OCT imaging has recently been proposed to describe end-stage atrophy in age-related macular degeneration (AMD) by international consensus and expected to be associated with a dense scotoma, but such functional evidence is lacking. This study sought to examine the visual sensitivity defects associated with cRORA and to determine OCT features associated with deep defects. Observational study.

Oct 28, 2023 | ophthalmologyscience.org | East Melbourne |Lauren Hodgson |Robyn Guymer

ABSTRACTTo examine the effectiveness of a targeted high-density microperimetry testing strategy for detecting visual sensitivity abnormalities in eyes with nascent geographic atrophy (nGA) when compared to standard central microperimetry testing. Observational study. Three-hundred and twenty-one eyes from 176 individuals with non-neovascular age-related macular degeneration (AMD).