Leonidas Chouliaras

Oct 28, 2024 | nature.com | Stacey L. Kigar |Leonidas Chouliaras |Noah S. Shapiro |George Savulich |Kaj Blennow |Henrik Zetterberg | +2 more

AbstractThe innate immune system plays an integral role in the progression of many neurodegenerative diseases. In addition to central innate immune cells (e.g., microglia), peripheral innate immune cells (e.g., blood monocytes, natural killer cells, and dendritic cells) may also differ in these conditions. However, the characterization of peripheral innate immune cell types across different neurodegenerative diseases remains incomplete.

Aug 22, 2023 | nature.com | Leonidas Chouliaras |John O’Brien

AbstractDementia is a leading cause of disability and death worldwide. At present there is no disease modifying treatment for any of the most common types of dementia such as Alzheimer’s disease (AD), Vascular dementia, Lewy Body Dementia (LBD) and Frontotemporal dementia (FTD). Early and accurate diagnosis of dementia subtype is critical to improving clinical care and developing better treatments.