Li Dong

Jan 14, 2025 | advanced.onlinelibrary.wiley.com | Li Dong |Yujia Lv |Nanosystems Chinese Academy |Chuyao Yu

1 Introduction Many retinal diseases cause severe vision impairment and can even lead to blindness. Visual disorders are generally categorized into optical blindness and neural blindness. While optical blindness, caused by conditions such as cataracts and keratopathy, can often be effectively treated with surgery, neural blindness is more challenging to address due to nerve damage. Unfortunately, current methods are inadequate for preventing the progression of such diseases.

Dec 24, 2024 | mdpi.com | Li Dong

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Lihuai Yu 1,†, Guangzhi Qiu 1,†, Xiaomu Yu 1, Jianwei Zhao 1, Jun Liu 1, Hongrong Wang 1 and Li Dong 1,2,* 1College of Animal Science and Technology, Yangzhou University, Yangzhou 215009, China 2Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China *Author to whom correspondence should be addressed.

Dec 15, 2024 | mdpi.com | Li Dong

3. Results and Analyses 3.1. Evaluation of the Effects of Rural Policy ImplementationAccording to Table 2 and Equations (3) and (4), values were assigned to the 20 policies, the PMC index and the policy concavity index of the policies to be evaluated were calculated, and the policies were graded according to the criteria for grading policy scores (Table 10).

Dec 11, 2024 | cell.com | Marziyeh Anari |Hamzeh Karimkhanloo |Shuai Nie |Li Dong |Gio Fidelito |Jacqueline A. Bayliss | +11 more

Keywords lipoprotein lipase very low-density lipoprotein tissue communication ceramide phospholipid lipid metabolism Research topic(s) CP: Metabolism Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined as steatotic liver disease in the presence of one or more cardiometabolic risk factors, including obesity, type 2 diabetes, and dyslipidemia.1 Metabolic dysfunction-associated steatohepatitis (MASH) is the more severe form of MASLD, and in addition to excess...

Dec 4, 2024 | biorxiv.org | Ang Li |Li Dong |Xuejun Li |Jianxun Yi

AbstractDifferent muscles exhibit varied susceptibility to degeneration in Amyotrophic Lateral Sclerosis (ALS), a fatal neuromuscular disorder. Extraocular muscles (EOMs) are particularly resistant to ALS progression and exploring the underlying molecular nature may deliver great therapeutic value. Reactive aldehyde 4-hydroxynonenal (HNE) is implicated in ALS pathogenesis and ALDH3A1 is an inactivation-resistant intracellular detoxifier of 4-HNE protecting eyes against UV-induced oxidative stress.