Lily Keane

Sep 10, 2024 | cell.com | Lily Keane |APC Microbiome Ireland |John Cryan |Jack Gleeson

Keywordsmicrobiomegut–brain axisgliomatumour microenvironmentmicrobial metabolitesThe cancer microbiomeThe human microbiota (see Glossary) is a complex ecosystem that symbiotically associates with barrier tissues found in the body [1]. The gut microbiome can interact and modulate host responses, especially the immune system [2], and the human gut microbiota consists of approximately 1000 species of bacteria as well as thousands of viruses and a less diverse plethora of archaea and fungi [3–5].

Mar 6, 2023 | nature.com | Lily Keane

Severe lower respiratory infections (sLRIs) are a group of illnesses that increase the risk of developing asthma. The increased prevalence of sLRIs in infants coincides with the development of the microbiota, and perturbing this axis increases sLRI severity. However, the mechanisms remain elusive.