Lin Luo

Oct 13, 2024 | nature.com | Belamy B. Cheung |Qian Wang |Janith A. Seneviratne |Andrew Gifford |Chelsea Mayoh |Lin Luo | +8 more

AbstractMYCN amplification predicts poor prognosis in childhood neuroblastoma. To identify MYCN oncogenic signal dependencies we performed N-ethyl-N-nitrosourea (ENU) mutagenesis on the germline of neuroblastoma-prone TH-MYCN transgenic mice to generate founders which had lost tumorigenesis. Sequencing of the mutant mouse genomes identified the Ring Finger Protein 121 (RNF121WT) gene mutated to RNFM158R associated with heritable loss of tumorigenicity.

Oct 3, 2024 | onlinelibrary.wiley.com | Yang Zhou |Lin Luo |Delong Zhang |Xingyu Wang

Introduction Dwarf crop resources serve as the foundation for crop dwarf breeding, and their identification constitutes the cornerstone of the 20th-century Green Revolution. Dwarfism imparts various advantages to crop varieties, including improved lodging resistance, denser growth, and increased harvest index, offering significant benefits for crop production (Mansfield and Mumm, 2014).

Sep 11, 2023 | arxiv.org | Chao Zhang |Min Lu |Lin Luo

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