location AMC

Nov 19, 2024 | academic.oup.com | location AMC |Van Schaik |van Royen-Kerkhof |van Wijk

Novel biomarkers are needed to guide therapy in idiopathic inflammatory myopathies (IIM). Expression of Siglec-1, a type I interferon biomarker, was examined in adult patients with IIM in relation to disease activity and treatment response. We analysed PBMC samples from 19 newly diagnosed adult IIM patients who participated in a phase-2 pilot study on efficacy of intravenous immunoglobulin (IVIG) monotherapy, and from 9 healthy controls.

Sep 12, 2024 | ejog.org | location AMC

KeywordsMaternal hypothermiaFetal bradycardiaPregnancySepsisObstetric managementGet full text accessLog in, subscribe or purchase for full access. References1. Lott, C. ∙ Truhlar, A. ∙ Alfonzo, A. ... European Resuscitation Council Guidelines 2021: cardiac arrest in special circumstancesResuscitation. 2021; 161:152-2192. Paal, P. ∙ Pasquier, M. ∙ Darocha, T. ... Accidental hypothermia: 2021 updateInt J Environ Res Public Health. 2022; 193.

May 22, 2024 | cell.com | Karl Alex Hedin |Max Nieuwdorp |location AMC |Ruben Vazquez-Uribe

HighlightsProteins and peptides derived from hormones hold huge potential for preventing and treating metabolic diseases. Challenges in administering peptide-based medicines include their short-lived nature, poor bioavailability, and reliance on methods such as injection, which might discourage people from medication adherence.

Jul 31, 2023 | academic.oup.com | location AMC |de Jong |Amsterdam UMC

By longitudinally following a large cohort of intercontinental travellers, this study highlights the importance of considering multiple risk factors to comprehend post-infectious Irritable Bowel Syndrome (PI-IBS). Stomach cramps, antibiotic use and nausea during travel were among the variables that predicted PI-IBS development following an episode of traveller’s diarrhoea.