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Jan 6, 2025 | 
onlinelibrary.wiley.com | Xinwei Hong |Lulu Xue |Yue Ma |Hang Fan
Conflicts of Interest The authors declare no conflicts of interest. References , , , , and . 2021. “The Influence of Person-Environment Fit on the Turnover Intention of Nurses in Jordan: The Moderating Effect of Psychological Empowerment.” Nursing Research and Practice 2021: 6688603. https://doi.org/10.1155/2021/6688603. , , , and . 1986. “Dynamics of Childhood and Adolescent Personality Traits and Adolescent Drug Use.” Developmental Psychology 22, no. 3: 403–414.
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Nov 21, 2024 | 
nature.com | Xuexiang Han |Mohamad-Gabriel Alameh |Rakan El-Mayta |Kelsey Swingle |Junchao Xu |Ningqiang Gong | +5 more
AbstractIonizable lipids largely determine the biocompatibility of lipid nanoparticles (LNPs) and the efficacy for mRNA delivery. Rational design and combinatorial synthesis have led to the development of potent and biodegradable ionizable lipids, yet methodologies for the stepwise optimization of ionizable lipid structure are lacking.
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Oct 1, 2024 | 
nature.com | Lulu Xue |Gan Zhao |Ningqiang Gong |Xuexiang Han |Zebin Xiao |Junchao Xu | +11 more
AbstractSystemic delivery of messenger RNA (mRNA) for tissue-specific targeting using lipid nanoparticles (LNPs) holds great therapeutic potential. Nevertheless, how the structural characteristics of ionizable lipids (lipidoids) impact their capability to target cells and organs remains unclear.
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Sep 11, 2024 | 
cleantechnica.com | Lulu Xue
Sign up for daily news updates from CleanTechnica on email. Or follow us on Google News!
Getting more zero-emission trucks on the road is an important transportation shift that is needed to reduce air pollution, protect public health and curb climate-harming emissions. But transforming the entire trucking industry is a challenging feat that will require the establishment of government policies with ambitious targets. Some jurisdictions have already begun.
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Sep 11, 2024 | 
evdriven.com | Lulu Xue
Sign up for daily news updates from CleanTechnica on email. Or follow us on Google News!Getting more zero-emission trucks on the road is an important transportation shift that is needed to reduce air pollution, protect public health and curb climate-harming emissions. But transforming the entire trucking industry is a challenging feat that will require the establishment of government policies with ambitious targets. Some jurisdictions have already begun.
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Sep 6, 2024 | 
thecityfix.com | Lulu Xue |Ke Chen
Getting more zero-emission trucks on the road is an important transportation shift that is needed to reduce air pollution, protect public health and curb climate-harming emissions. But transforming the entire trucking industry is a challenging feat that will require the establishment of government policies with ambitious targets. Some jurisdictions have already begun. For example, new EU legislation requires that by 2040, heavy-duty vehicles reduce carbon emissions by 90% compared to 2019 levels.
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Sep 4, 2024 | 
wri.org | Lulu Xue |Ke Chen
Getting more zero-emission trucks on the road is an important transportation shift that is needed to reduce air pollution, protect public health and curb climate-harming emissions. But transforming the entire trucking industry is a challenging feat that will require the establishment of government policies with ambitious targets. Some jurisdictions have already begun. For example, new EU legislation requires that by 2040, heavy-duty vehicles reduce carbon emissions by 90% compared to 2019 levels.
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Jul 9, 2024 | 
nature.com | Xuexiang Han |Ningqiang Gong |Lulu Xue |Majed Ghattas |Junchao Xu |Gan Zhao | +8 more
AbstractLipid nanoparticles (LNPs) are widely used for mRNA delivery, with cationic lipids greatly affecting biodistribution, cellular uptake, endosomal escape and transfection efficiency. However, the laborious synthesis of cationic lipids limits the discovery of efficacious candidates and slows down scale-up manufacturing.
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Jul 1, 2024 | 
nature.com | Ningqiang Gong |Rakan El-Mayta |Lulu Xue
AbstractIn situ cancer vaccination refers to any approach that exploits tumour antigens available at a tumour site to induce tumour-specific adaptive immune responses. These approaches hold great promise for the treatment of many solid tumours, with numerous candidate drugs under preclinical or clinical evaluation and several products already approved. However, there are challenges in the development of effective in situ cancer vaccines.
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Jun 28, 2024 | 
wri.org | Ke Chen |Lulu Xue
Addressing the demand side, particularly the concerns of cost-conscious and less technology-savvy small- and medium-sized enterprises (SMEs), is critical for the future uptake of zero-emission trucks (ZETs).
