Luping Liu

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma |Feng Wang |Dan Zhang |Luping Liu | +17 more

Editor’s summaryCD8+ T cells are a critical part of antitumor immunity and depend on metabolites including glucose to maintain their function. Here, Liu et al. have evaluated targeting glucose transport 10 (GLUT10) as a way to increase CD8+ T cell function by disrupting the competitive binding of lactic acid that increased glucose uptake, thereby increasing proliferation and antitumor capacity.