Loretah Chibaya

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma

Because of a production error in the Research Article “ MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells ” by S. Perrin., the references cited in the Supplementary Materials were missing from the published article. These references have been added to the References and Notes list as numbers 57 to 68 in the PDF and the HTML, and the Supplementary Materials PDF has been updated with these reference numbers.

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma |Tomokazu Sumida

Editor’s summaryRegulatory T cells (Tregs) are known to be dysfunctional in autoimmune diseases, but the cause of this dysfunction has not been fully elucidated. Here, Sumida et al.

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma |Liyin Zhang |Hua Zhang

Editor’s summaryLung regeneration after injury or transplantation is limited by fibrosis. Ma et al. showed that a subset of glycolytic endothelial cells that express Ras homolog family member J (Rhoj) was responsible for impaired lung regeneration and intussusceptive angiogenesis or split blood vessels in response to injury.

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma |Feng Wang |Dan Zhang |Luping Liu | +17 more

Editor’s summaryCD8+ T cells are a critical part of antitumor immunity and depend on metabolites including glucose to maintain their function. Here, Liu et al. have evaluated targeting glucose transport 10 (GLUT10) as a way to increase CD8+ T cell function by disrupting the competitive binding of lactic acid that increased glucose uptake, thereby increasing proliferation and antitumor capacity.